Tumor Immune MicroEnvironment cell composition DataBase

TIMEDB is an online human tumor immune micro-environment (TIME) cell-type composition database. TIMEDB provides TIME cell-type composition data estimated from bulk expression profiles, with automate analysis and interactive visualization. Please cite our NAR paper.

TIMEDB has three key features:

  • Curated TIME database of 39706 samples and 546 datasets across 43 cancers, including bulk RNA data, clinical data, TIME cell-type composition estimated by 10 state-of-the-art tools, C1-C6 subtyping data, immunomodulatory gene expression profiles, etc.
  • Automatic interfaces of 21 tumor immune microenvironment analyses, including TIME cell-type composition estimation, subtyping, survival, correlation, etc.
  • Interactive visualizations of clinical features, TIME cell-type composition, patient subtyping, survival, and correlation profile from the database or analysis.


Human Gut Metagenomics.png

Human tumor immune micro-environment database

Curated databse with over 39706 samples of RNA-seq across 43 cancers , immune infliatration fraction, immune subtype annotation data.

Automatic analyses

10 online tumor immune microenvironment analysis category 21 analyses.

Human Gut Metagenomics.png



Nov. 19, 2022, 09:00 a.m.

Our journal is published in NAR successfully. Please check here for details.

V1.2.2 update

Oct. 17, 2022, 12:00 a.m.

We rewrote tutorial pages and added some user guidance.

V1.2.1 update

Oct. 6, 2022, 12:00 a.m.

We adjusted layout of tutorial pages and fixed some bugs.

V1.2.0 update

Sep. 27, 2022, 08:00 p.m.

We created links for bug reporting and fixed bugs of the search bar in tutorial pages. We also optimized the UMAP visualization for batch effect analysis.

V1.1.9 update

Sep. 26, 2022, 12:00 a.m.

We rewrited tutorial pages and fixed some known bugs.

V1.1.8 update

Sep. 19, 2022, 10:00 a.m.

We fixed some cell-type composition landscape plot bugs.

V1.1.7 update

Sep. 5, 2022, 9:10 a.m.

We adjusted smoothly transitioning numbers and fixed some known bugs.

V1.1.6 update

Aug. 6, 2022, 12:50 a.m.

We fixed known bugs and improved tutorial pages.

V1.1.5 update

July. 25, 2022, 5:45 p.m.

More pipelines have passed testing and been put into production.

V1.1.4 update

June. 30, 2022, 7:50 p.m.

We improved the database schema. It is possible for users to check more than one data visualization for a single analysis task.

V1.1.3 update

May. 15, 2022, 3:10 p.m.

We rewrited the back-end logic for task results checking and beautified the workspace page.

V1.1.2 update

Apr. 30, 2022, 12:50 a.m.

We added API to track website visiting statistics.

V1.1.1 update

Mar. 30, 2022, 9:30 a.m.

We created the download page. Now users can easily find and download all data files available in a single page.

V1.1.0 update

Feb. 26, 2022, 4:10 p.m.

we uploaded more data after rechecking the accuracy and validation of our database.

V1.0.9 update

Feb. 15, 2022, 8: 30 p.m.

We added new functions that users can submit the demo tasks or check the analysis results of demo tasks to get familiar with the task submission procedure.

V1.0.8 update

Jan. 30, 2022, 9:20 a.m.

We created the tutorial page.

V1.0.7 update

Dec. 28, 2021, 12:30 p.m.

Analysis module categorization & Submit page logic rewritting.

V1.0.6 update

Dec. 1, 2021, 11:25 p.m.

We fixed known bugs.

V1.0.5 update

Nov. 5, 2021, 10:20 p.m.

We added new functions. Users are allowed to create their own datasets using samples from our database.

V1.0.4 update

Nov. 2, 2021, 5:30 p.m.

More analysis modules have passed testing.

V1.0.3 update

Oct. 15, 2021, 9:00 p.m.

We completed several analysis modules with data visualizations available.

V1.0.2 update

Seq. 18, 2021, 10:00 p.m.

Clinical data and RNA data uploading & Database recheck.

V1.0.1 update

Sep. 1, 2021, 9:30 p.m.

we beautified home page and added the contact page and the privacy terms page.

Add database pages

Aug. 5, 2021, 6:05 p.m.

Cancers, datasets and samples tables are ready to display.

Project initialization

July. 1, 2021, 12:30 p.m.

Main frame completion & Platform deployment.

Please kindly send errors if any to xywang85-c@my.cityu.edu.hk. Many thanks for your support.